Smith and Williams' Introduction to the Principles of Drug Design and Action

As knowledge of biological systems has expanded and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. This unique insight has revolutionized the process of drug development for specific disease states. The fourth edition of this popular textbook provides a thorough introduction to the principles of rational drug design, including both novel and established approaches. it adopts a 'from the bench to the marketplace' approach, using real examples where possible. In addition to a comprehensive update of the previous edition, new advances in molecular techniques, biotechnological applications and computer-aided design have been added.