Innovative Drug Synthesis

Discover the cutting–edge science driving the medicinal chemistry and synthesis of the latest drugs Continuing the tradition of the acclaimed prior volumes on drug synthesis, Innovative Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and related disciplines come together to produce successful medicines. This book covers all aspects of the medicinal chemistry of the latest drugs, and the cutting–edge science associated with them. With authoritative coverage by distinguished editors and authors analyzing the pros and cons of different synthetic routes, the book demystifies the process of modern drug discovery for practitioners and researchers Other highlights include: Summary of respective disease area, important properties and SAR (structure–activity relationship), and chemical synthesis routes / options for each covered drug A step–by–step breakdown of today?s drug discovery process for professionals and students Chapters on drugs that have achieved breakthrough therapy designation such as sofosbuvir, palbociclib and more Innovative Drug Synthesis shows that whether drug synthesis is in early development or the process stage, the ability to design elegant and economical synthetic routes is often a major factor making a drug a commercial winner. Easy to follow and stacked with valuable information on the present and future direction of medicinal chemistry, Innovative Drug Synthesis paints a clear and complete picture of this complex subject.