Transporters and Drug-Metabolizing Enzymes in Drug Toxicity

This book provides a comprehensive and up-to-date coverage of the relationship between drug metabolism enzymes and transporters on drug toxicity. It brings together the scientific disciplines of drug metabolism and toxicology, with a focus on the role of biotransformation on drug toxicity and as a major factor for species and individual differences.  In addition, the author describes promising experimental approaches to accurately assess human drug toxicity via the incorporation of human-specific drug metabolism in toxicity assays.