Antimicrobial Peptides: Discovery, Design and Novel Therapeutic Strategies
Guangshun Wang
ISBN: 9781786390394
Vydavateľstvo: CABI International
Rok vydania: 2017
Vydanie: 2nd Edition
Väzba: Hardback
Počet strán: 288
Pôvodná cena: 141,02 €
Výstavná cena:
119,87 €(t.j. po zľave 15%)
(Cena je uvedená vrátane 10% DPH)
Katalógová cena: 105 GBP
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Antimicrobial peptides (AMPs) have attracted extensive research attention worldwide. Harnessing and creating AMPs synthetically has the potential to help overcome increasing antibiotic resistance in many pathogens. This new edition lays the foundations for studying AMPs, including a discovery timeline, terminology, nomenclature and classifications. It covers current advances in AMP research and examines state-of-the-art technologies such as bioinformatics, combinatorial libraries, high-throughput screening, database-guided identification, genomics and proteomics-based prediction, and structure-based design of AMPs.Thoroughly updated and revised, this second edition contains new content covering: defensins; cathelicidins; anti-MRSA, antifungal, antiviral, anticancer and antibiofilm strategies; combined treatments; adjuvants in vaccines; advances in AMP technologies that cover surface coating to prevent biofilm formation; nanofiber encapsulation technologies for delivery and sustained release; and understanding innate immunity and the basis for immune boosting to overcome obstacles in developing AMPs into therapeutic agents.Written and reviewed by a group of established investigators in the field, Antimicrobial Peptides is a valuable resource for postgraduate students, researchers, educators, and medical and industrial personnel.